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  <url>
    <loc>https://www.ruthfranklinlab.com/research</loc>
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    <lastmod>2026-03-07</lastmod>
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      <image:title>Research</image:title>
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      <image:title>Research</image:title>
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  <url>
    <loc>https://www.ruthfranklinlab.com/team</loc>
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    <lastmod>2025-08-04</lastmod>
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      <image:title>Team - Alan Baez Vazquez</image:title>
      <image:caption>Graduate Student Alan was born in Tlaquepaque, Jalisco, Mexico before moving to the beautiful state of Maine. He attended the University of Maine in Orono where he earned a B.S. in Biochemistry with highest honors. At the University of Maine, Alan worked within the lab of Dr. Julie Gosse to determine the molecular mechanism behind the antimicrobial triclosan’s inhibition of adaptive and innate immune cell function. Alan has also worked at the Jackson Laboratory under the guidance of Dr. Dan Skelly to study how genetic background influences immune cell heterogeneity within mouse visceral adipose tissue. After finishing his undergraduate career, Alan enrolled within the Molecules, Cells, and Organisms (MCO) PhD training program at Harvard University where he eventually joined the Franklin lab. Within the Franklin lab, Alan will explore how regenerative and immune programs differ between homeostatic and diseased tissues. Outside of the lab, Alan loves to hike (and heavily recommends Acadia national park), cook, and play video games.</image:caption>
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      <image:title>Team - Shahinoor Begum</image:title>
      <image:caption>Lab Manager Shahinoor earned bachelor’s and master’s degrees in pharmacy from the University of Dhaka, Bangladesh. She was later awarded an MS degree in Biotechnology from the Johns Hopkins University. She also studied electrical signaling in nervous and muscular systems of mouse models and mechanical signaling in cells at Harvard University under Professor Adam Cohen. Prior to that, Shahinoor was studying extracellular matrix proteins and the mechanisms of cell adhesion and migration in the context of cancer metastasis at MIT under Professor Richard Hynes. Outside of the lab, she likes gardening and growing exotic vegetables from her homeland. She also enjoys studying Indian history and reading nonfiction Bengali and Indian titles.</image:caption>
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      <image:title>Team - Martha Castro</image:title>
      <image:caption>Graduate Student Martha was born and raised in California and received her B.A. from Pomona College in Molecular Biology. At Pomona, she worked with Dr. Daniel Martínez to characterize a new species of hydra, and conducted summer research in the labs of Dr. Sheri Krams and Dr. Olivia Martinez at Stanford University and Dr. Douglas Melton at Harvard University. After graduation, Martha ventured to Stockholm, Sweden for a Fulbright research year in the Malin Flodström-Tullberg group at Karolinska Institutet. There she explored the effects of JAK/STAT inhibitors on interferon-induced antiviral defense in human intestinal epithelial cells. In the Franklin lab, Martha is excited to study the relationship between macrophages and progenitor cells during damage and repair. During her free time, she enjoys swimming and running, trying new recipes, and knitting.</image:caption>
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      <image:title>Team - Max Hauptschein</image:title>
      <image:caption>Graduate Student Max received his B.A. from the University of California, Berkeley with a major in Molecular and Cell Biology. At UC Berkeley, he conducted research under the guidance of Dr. Teresa Puthussery to characterize a previously unidentified retinal ganglion cell type in primates. Following graduation, Max worked as a research assistant in the laboratory of Dr. Anne Brunet, investigating how T cells and microglia affect neural stem cell function in the aged brain. In the Franklin lab, Max is excited to study communication between immune and non-immune cells in the context of tissue damage and repair. Specifically, the roles of interferon signaling in regulating epithelial populations in the lungs. Outside of lab, Max enjoys playing and watching sports, trying new restaurants, and visiting art museums.</image:caption>
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      <image:title>Team - Dr. Daisy Hoagland</image:title>
      <image:caption>Postdoctoral Fellow Daisy received her B.S. from the University of Vermont where she majored in Microbiology and minored in Community and International Development. At UVM, Daisy worked in the laboratory of Dr. Yvonne Janssen-Heininger where she studied the role of different cytokines in allergic asthma. Before beginning graduate school, she spent a year with AmeriCorps working at a STEM mentorship nonprofit in the Bay Area of California. Daisy completed her Ph.D. in Dr. Benjamin tenOever’s laboratory at the Icahn School of Medicine at Mount Sinai in New York City where she studied the host response to SARS-CoV-2 infection to inform the development of therapeutics by characterizing the golden hamster model. Daisy also spent time studying influenza and innate immunity. She is excited to study mechanisms of disease tolerance and continue learning about viruses in the Franklin laboratory. Outside of lab, Daisy enjoys baking, hiking, and reading a good book.</image:caption>
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      <image:title>Team - Sunny Lin</image:title>
      <image:caption>Graduate Student Sunny obtained her B.A. from Boston University, majoring in Biology with a specialization in Cell, Molecular Biology, and Genetics, and minoring in Japanese Literature. She had the opportunity to study abroad in Tokyo, Japan her junior year, where she spent the majority of her time satisfying her sweet tooth. During her undergraduate years, Sunny worked in the laboratory of Dr. Mikael Pittet, investigating the roles of myeloid cells, specifically macrophages, in tumor suppression. Prior to pursuing her graduate studies, she spent two years working in Dr. Todd Golub’s laboratory at the Broad Institute screening for in vivo cancer dependencies. Now, in the Franklin lab, Sunny is thrilled to delve back into the world of macrophage research, with a particular focus on investigating the mechanisms of macrophage turnover during homeostasis. Outside of lab, Sunny enjoys exploring new cafes with friends, indulging in mystery shows/novels, and attempting to recreate those Japanese desserts she fell in love with during her time abroad!</image:caption>
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      <image:title>Team - Dr. Alexander Mann</image:title>
      <image:caption>Postdoctoral Fellow Alex received a B.S. in Microbiology at the University of Oklahoma. He then completed a Ph.D. in Immunology at Harvard Medical School working in the laboratory of Diane Mathis and Christophe Benoist. During his Ph.D. work, Alex studied the roles of gamma delta T cells in models of autoimmunity and tissue injury. This latter part of his Ph.D. work sparked a broader interest in how the immune system responds to tissue damage and what roles it can play in the restoration of tissue homeostasis. Outside of the lab Alex enjoys cooking, hiking, and generally exploring New England.</image:caption>
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      <image:title>Team - Nithya Medam</image:title>
      <image:caption>Undergraduate Student Nithya is a California native hailing from the northern Central Valley region. She is an undergraduate at Harvard College, studying Human Developmental and Regenerative Biology with a secondary in Sociology. Nithya is thrilled to join the Franklin Lab, where she’ll be investigating macrophage-mediated regulation of tissue homeostasis and tumor progression. In her spare moments, she enjoys playing frisbee, solving the NY Times mini, and spending time outdoors.</image:caption>
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      <image:title>Team - Dr. Ruth A. Franklin</image:title>
      <image:caption>Principal Investigator Ruth received her B.A. from Bowdoin College in Brunswick, Maine where she majored in Biology and minored in Sociology. At Bowdoin, she worked in the developmental biology lab of Dr. Nicole Theodosiou studying hindgut and spleen development in the chicken embryo. She then moved to California to thaw out and worked in a cell biology lab at Scripps Research Institute exploring strategies to normalize pathogenic angiogenesis associated with eye disease and the incurable brain tumor, glioblastoma multiforme. Ruth moved back to the East Coast to attend Weill Cornell Graduate School of Medical Sciences in New York City. There, she joined the lab of Dr. Ming Li at Memorial Sloan Kettering Cancer Center and characterized the lineage and function of tumor-associated macrophages in the development and progression of breast cancer. As a postdoc in the lab of Dr. Ruslan Medzhitov at Yale School of Medicine, Ruth extended her interests in macrophage biology to study their homeostatic functions. Her work demonstrated how relative ratios of different cell types within tissues are regulated through the exchange of growth factors. In Ruslan’s lab she also identified a number of secreted factors produced by macrophages in response to stress. These molecules likely have important functions in both stress conditions and inflammation. In her free time, Ruth loves cooking, baking, and spending time with her family.</image:caption>
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  </url>
  <url>
    <loc>https://www.ruthfranklinlab.com/publications</loc>
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    <priority>0.75</priority>
    <lastmod>2026-01-16</lastmod>
  </url>
  <url>
    <loc>https://www.ruthfranklinlab.com/news</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2026-01-14</lastmod>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>End of summer BBQ 2025</image:caption>
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      <image:title>News - July 2025:</image:title>
      <image:caption>Fantastic GRC in Lucca, Italy on Lung Development, Injury and Repair! Complete with Alan winning a poster prize, congrats!!</image:caption>
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      <image:title>News - July 2025:</image:title>
      <image:caption>Paper celebrations continue!!</image:caption>
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      <image:title>News - May 29, 2025:</image:title>
      <image:caption>Graduation day! Today was a happy day! Very proud of Patricia and sending best wishes as she takes the next step in her career!!</image:caption>
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      <image:title>News - May 9, 2025:</image:title>
      <image:caption>PAPER ACCEPTANCE DAY!!!! So grateful for the incredible members of my lab who made it happen—especially Daisy and Patricia, and all other coauthors for their contributions along the way!</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>Celebrating Dr. Rodríguez-Morales!</image:caption>
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      <image:title>News - May 2025:</image:title>
      <image:caption>Another Franklin lab first!! Huge congratulations to Dr. Patricia Rodríguez-Morales on her thesis defense!!</image:caption>
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      <image:title>News - April 2025:</image:title>
      <image:caption>Honored to be back at Yale for the Grad Student Symposium! Had an amazing time meeting the current students and fellow speakers!</image:caption>
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      <image:title>News - Behind the scenes at the JoVE recording</image:title>
      <image:caption>Franklin lab video debut!</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>Happy New Year!! 2025 is sure to be an exciting year!</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>News - Alex taking his turn at the lab retreat “Fireside Chat”</image:title>
      <image:caption>Talking science is better by a fire (this new lab tradition is a keeper!)</image:caption>
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      <image:title>News - November 2024:</image:title>
      <image:caption>Franklin lab retreat in North Conway, NH</image:caption>
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      <image:title>News - October 2024:</image:title>
      <image:caption>Was an honor to serve as a PhD thesis examiner for Université Paris-Saclay student, Kevin Mulder! Congratulations Dr. Mulder on the beautiful work!</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>SCRB Retreat at the New England Aquarium; Congrats to Alan for winning the Best Poster Prize!!</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>Summer BBQ 2024!</image:caption>
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      <image:title>News - July 2024:</image:title>
      <image:caption>Daisy crushing her talk at the Society for Mucosal Immunology Meeting ICMI 2024 in Copenhagen, Denmark!</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>Immunology Department Retreat, Falmouth, MA</image:caption>
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      <image:title>News - June 3, 2024:</image:title>
      <image:caption>New PhD candidate in the lab! Congrats to Martha for passing her qualifying exam!</image:caption>
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      <image:title>News - First AAI meeting was a success!</image:title>
      <image:caption>Congratulations to Patricia for receiving the ThermoFisher Trainee Achievement Award and giving an excellent presentation at AAI!</image:caption>
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      <image:title>News - May 2024:</image:title>
      <image:caption>Extremely honored to receive the AAI ASPIRE Award for Outstanding Early Career Achievement in Immunology! Chicago, IL (pictured with Akiko Iwasaki)</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>Lab celebratory dinner!</image:caption>
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      <image:title>News - March 18, 2024:</image:title>
      <image:caption>Another proud PI moment! Celebrating Sunny passing her qualifying exam!</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>Happy New Year from the Franklin lab! Expecting big things in 2024!</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>Lab apple picking! Thankful for these stellar scientists!</image:caption>
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      <image:title>News - Amazing International Cytokine &amp; Interferon Society meeting in Athens! Proud to be a member of the ICIS community!</image:title>
      <image:caption>Photo in place of Daisy rocking her poster presentation at the conference! (Temple of Hephaistos in background)</image:caption>
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      <image:title>News - October 2023:</image:title>
      <image:caption>Honored to accept the ICIS-Regeneron New Investigator Award for Excellence in Cytokine &amp; Interferon Research! Athens, Greece (pictured with George Yancopoulos)</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>Franklin lab summer BBQ!</image:caption>
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      <image:title>News - August 2023:</image:title>
      <image:caption>Proud of summer student, Julia, for a fantastic summer research project!</image:caption>
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      <image:title>News - June 2023:</image:title>
      <image:caption>Lab celebratory dinner! So much to celebrate as the lab turns 3! Two new grad students (Martha &amp; Sunny), summer student from Bowdoin (Julia, happy bday!), first lab NIH grant (woop!), trainee talk award (Patricia), and just general awesomeness of this team!</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>Alan presenting his work at the Immunology dept. retreat!</image:caption>
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      <image:title>News - June 2023:</image:title>
      <image:caption>Another successful Immunology Dept. retreat! Huge congrats to Patricia for winning “Best Trainee Talk” award! (pictured here with Arlene Sharpe)</image:caption>
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      <image:title>News - June 2023:</image:title>
      <image:caption>Alicia, we will miss you!! Sad to say goodbye to my first lab member, Alicia! Unbelievably grateful for all Alicia’s help as I started the lab! Wishing you the best of luck in your future adventures!</image:caption>
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      <image:title>News - May 2023:</image:title>
      <image:caption>Congrats McKenna!! The first undergrad to complete a Senior Thesis in the Franklin lab has graduated! Looking forward to McKenna’s future success as she moves on to UPenn for graduate school!</image:caption>
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      <image:title>News - April 2023:</image:title>
      <image:caption>The Franklin lab at 11,000 feet! Keystone Symposia: From First Breath: Lung Development, Infection, Repair &amp; Aging/ Inflammation in the Lung: Friend or Foe in Viral Infections? Snowbird, UT</image:caption>
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      <image:title>News - December 2022:</image:title>
      <image:caption>Happy Holidays from the Franklin lab!</image:caption>
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      <image:title>News - October 2022:</image:title>
      <image:caption>It’s not fall in New England without apple picking!!</image:caption>
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      <image:title>News - September 2022:</image:title>
      <image:caption>End of summer BBQ!</image:caption>
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      <image:title>News - July 3, 2022:</image:title>
      <image:caption>Had a wonderful time celebrating the marriage of Alex and Brinda! (the Franklin lab cleans up nicely!)</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>Top notch color coordination at the Immunology dept. retreat!</image:caption>
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      <image:title>News - June 2022:</image:title>
      <image:caption>Enjoying the sun at the Harvard Immunology departmental retreat! Cape Cod, MA</image:caption>
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      <image:title>News - June 2022: Happy birthday McKenna!</image:title>
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      <image:title>News - May 3, 2022:</image:title>
      <image:caption>More congrats for Patricia!! Happy to celebrate Patricia passing her qualifying exam! Woohoo!</image:caption>
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      <image:title>News - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>News - March 7, 2022:</image:title>
      <image:caption>Proud PI moment! Popping some bubbly to celebrate Alan passing his qualifying exam—a Franklin Lab first!</image:caption>
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      <image:title>News - December 2021:</image:title>
      <image:caption>Happy Holidays from the Franklin Lab! 2021 was a crazy year, but so excited to see what 2022 has in store! Photo: Holiday Lunch at Time-Out/Trillium brewery</image:caption>
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      <image:title>News - October 2021:</image:title>
      <image:caption>Welcome to our first postdoc, Daisy and undergrad, Emily! Love watching the lab grow! Photo: Post-grant submission celebratory BBQ</image:caption>
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      <image:title>News - July 2021:</image:title>
      <image:caption>Ecstatic to officially welcome the first two Franklin lab grad students to the team! Can’t wait to see what Patricia &amp; Alan will accomplish! Photo: Chiu/Franklin/Jackson Tri-lab picnic</image:caption>
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      <image:title>Teaching - Make it stand out</image:title>
      <image:caption>Last class of FYSEMR 53D! THANK YOU to this amazing group of first-year students for a fantastic semester!! Fall ‘24</image:caption>
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